Obstetrics and Gynecology
Mandana Mansour Ghanaei; Sude Amir Afzali; Ali Morady; Roxana Mansour Ghanaie; Seyed Mohammah Asghari Ghalebin; Elahe Rafiei; Roya Kabodmehri
Volume 7, Issue 3 , January and February 2022, , Pages 177-185
Abstract
Background & Objective: Accordingly, this study aimed to assess pregnancy outcomes and pathological findings of the placenta caused by intrauterine growth restriction (IUGR) with or without pre-eclampsia (PE).Materials & Methods: This cohort study was conducted on two groups: Group I was ...
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Background & Objective: Accordingly, this study aimed to assess pregnancy outcomes and pathological findings of the placenta caused by intrauterine growth restriction (IUGR) with or without pre-eclampsia (PE).Materials & Methods: This cohort study was conducted on two groups: Group I was PE-induced IUGR (PE-IUGR), and group II was idiopathic IUGR (I-IUGR). Pregnancy and neonatal outcomes were evaluated in both groups. The placental assessment was also performed based on pathological findings. Data were compiled and analyzed by SPSS 21. An analytical study was conducted on the groups based on t (or non-parametric Mann-Whitney), chi-square, and Fisher’s exact tests.Results: The findings of this study showed that maternal age, body mass index (BMI), the incidence of preterm delivery, and low birth weight were higher in the PE-IUGR group (P < /em><0.001 in all) than in the I-IUGR group, and the difference was statistically significant. Additionally, circulatory disorders and impaired anomalies were higher in the PE-IUGR group (P < /em>>0.001) than in the I-IUGR group.Conclusion: Placental disorders and reduced blood flow to the fetus due to placental disorders might lead to low birth weight and preterm delivery.
Obstetrics and Gynecology
Mandana Mansour Ghanaei; Effat Ebadollahi Nodeh; Seyed Mohammah Asghari Ghalebin; Seyedeh Hajar Sharami; Katayoun Haryalchi
Volume 7, Issue 2 , September and October 2021, , Pages 83-88
Abstract
Background & Objective: Opioids that are used during anesthesia may prolongate intestinal peristalsis. This study aimed to examine the effect of oral methylnaltrexone (OMNTX) on ileus after hysterectomy.Materials & Methods: This study was performed as a randomized, double-blind screening for ...
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Background & Objective: Opioids that are used during anesthesia may prolongate intestinal peristalsis. This study aimed to examine the effect of oral methylnaltrexone (OMNTX) on ileus after hysterectomy.Materials & Methods: This study was performed as a randomized, double-blind screening for an elective abdominal hysterectomy at Alzahra Hospital in Rasht, Iran; 33 patients were assigned to the OMNTX group (25 mg) and 33 to the placebo group using the random block method. Patients were asked and recorded about gas passing, constipation, vomiting, itching, and urinary retention.Results: There was a significant difference in the meantime of initiation of intestinal sound (P < /em>=0.039) and constipation (P < /em>=0.62) between the two groups. There was a positive correlation coefficient in the placebo group (P < /em>=0.02) between the hours of surgery and the time of initiation of bowel movements after the surgery. Still, there was not in the OMNTX group (P < /em>=0.0001). The mean onset of bowel sounds after the surgery was not related to age (P < /em>=0.599) and the duration of surgery significantly (P < /em>=0.926).Conclusion: It is possible that OMNTX before the surgery can trigger bowel sounds sooner after the surgery and prevent ileus.
Maternal Fetal Medicine
mandana Mansour Ghanaie; Roxana Mansour Ghanaie; Seyed Mohammad Asgari Galebin; Seyedeh Hajar Sharami; Mojgan Mohebalizade
Volume 7, Issue 1 , September and October 2021, , Pages 25-31
Abstract
Background & Objective: Nucleated red blood cells (NRBCs) enter the circulation in response to hypoxia, but it remains unknown how physiological delivery without fetal distress can change the NRBC level. Accordingly, in the present study, we compared the mean NRBCs per white blood cell (WBC) in the ...
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Background & Objective: Nucleated red blood cells (NRBCs) enter the circulation in response to hypoxia, but it remains unknown how physiological delivery without fetal distress can change the NRBC level. Accordingly, in the present study, we compared the mean NRBCs per white blood cell (WBC) in the umbilical cord of normal vaginal delivery (NVD) with cesarean section (C/S). To compare the mean NRBCs per WBC within umbilical cord in normal term newborns who were born by NVD with those delivered by C/S. Methods: This case-control study was conducted for 305 neonates in two different groups, i.e., NVD (case) and C/S (control) groups. The blood samples were taken from umbilical veins to evaluate fetal NRBCs and WBC count after recording their demographic characteristics. Finally, all data were assessed using SPSS 16.Results: The average age of mothers was 25.79±5.35 years. The average Apgar score of neonates was 8.23±0.6. The average NRBC count was 4.63±5.2. There was no significant difference in maternal age, parity, neonatal weight, and NRBC count per 100 WBCs between the two groups. Conclusion: In the present study, the mean NRBC count within the umbilical cord of neonates born by elective C/S was less than those delivered by NVD, although this difference was not significant.